Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 9 3
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 10 10
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 9 3
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 7 6
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 9 4
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 39 22
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 18 12
CD40 P25942 CD40 molecule 0.85 0.396 0.846 9 3
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 13 6
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 19 8
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 9 8
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 7 3
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 5 1
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885 1 1
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731 24 18
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 12 9
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 10 8
IL27 Q8NEV9 interleukin 27 0.78 0.457 0.808 10 11
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 16 13
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885 7 3