Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 5
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692 3
HMGCL P35914 3-hydroxy-3-methylglutaryl-CoA lyase Enzyme 2.6E-06 0.691 0.462 1
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
HMGCS1 Q01581 3-hydroxy-3-methylglutaryl-CoA synthase 1 1.00 0.769 0.346 3
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 3
HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase 1.1E-08 0.644 0.538 1
BDH1 Q02338 3-hydroxybutyrate dehydrogenase 1 Enzyme 7.6E-08 0.729 0.423 2
OXCT1 P55809 3-oxoacid CoA-transferase 1 Enzyme 4.7E-03 0.686 0.423 3
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
XRN2 Q9H0D6 5'-3' exoribonuclease 2 0.35 0.821 0.269 1
ALAS1 P13196 5'-aminolevulinate synthase 1 Enzyme 0.11 0.705 0.462 5
ALAS2 P22557 5'-aminolevulinate synthase 2 Enzyme 1.00 0.606 0.577 4
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 2
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 4
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 8
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538 5
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 6
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 8
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 3
PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Kinase 4.9E-07 1.000 0.038 1
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 9
AKAP1 Q92667 A-kinase anchoring protein 1 Enzyme 0.74 0.678 0.577 1