Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 16
AXIN1 O15169 axin 1 0.41 0.559 0.577 8
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 23
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846 9
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 28
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808 5
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 15
MAX P61244 MYC associated factor X Transcription factor 0.83 0.553 0.769 5
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808 12
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808 8
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731 8
PIK3R2 O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 1.6E-02 0.551 0.808 4
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654 8
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808 10
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731 12
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 27
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846 8
SPOP O43791 speckle type BTB/POZ protein 1.00 0.597 0.500 4