Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769 46 41
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 41 26
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
CASC15 cancer susceptibility 15 0.603 0.577 35 41
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.647 0.615 31 41
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
CLEC16A Q2KHT3 C-type lectin domain containing 16A 0.28 0.612 0.654 29 38
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32
PNKD Q8N490 PNKD metallo-beta-lactamase domain containing 4.1E-08 0.615 0.615 28 17
PVT1 Pvt1 oncogene 0.495 0.731 27 31
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 27 23
KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 1.00 0.592 0.731 25 15
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731 24 26
HCP5 Q6MZN7 HLA complex P5 0.595 0.808 23 17
MIR3936HG MIR3936 host gene 0.861 0.269 22 18