Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 8
ACTC1 P68032 actin alpha cardiac muscle 1 Cellular structure 0.74 0.610 0.538 2
ATF2 P15336 activating transcription factor 2 Transcription factor 0.99 0.551 0.808 4
ACSM3 Q53FZ2 acyl-CoA synthetase medium chain family member 3 Enzyme 1.4E-14 0.623 0.615 2
ADAMTS16 Q8TE57 ADAM metallopeptidase with thrombospondin type 1 motif 16 Enzyme 4.5E-04 0.711 0.346 2
ADD1 P35611 adducin 1 Cellular structure 0.99 0.612 0.615 2
ADD2 P35612 adducin 2 Cellular structure 1.00 0.678 0.615 1
ADD3 Q9UEY8 adducin 3 Cellular structure 1.00 0.641 0.500 1
ADORA1 P30542 adenosine A1 receptor G-protein coupled receptor 1.5E-02 0.578 0.692 13
ADA P00813 adenosine deaminase Enzyme 2.9E-12 0.440 0.885 11
ADCY5 O95622 adenylate cyclase 5 1.00 0.617 0.577 2
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846 8
ADRA2A P08913 adrenoceptor alpha 2A G-protein coupled receptor 8.2E-04 0.578 0.615 11
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846 1
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 11
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769 12
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 7
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 12
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64