Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.34 0.287 0.966 1330 16
IL1B P01584 interleukin 1 beta 0.13 0.312 0.931 1035 15
IL10 P22301 interleukin 10 6.5E-03 0.320 0.931 961 17
IFNG P01579 interferon gamma 0.47 0.323 0.897 901 6
EGFR P00533 epidermal growth factor receptor 0.50 0.325 0.862 892 88
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.38 0.321 0.828 891 108
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 871 92
APOE P02649 apolipoprotein E 1.7E-03 0.352 0.931 770 39
LMNA P02545 lamin A/C 1.00 0.406 0.724 727 213
IGF1 P05019 insulin like growth factor 1 0.29 0.355 0.828 715 24
MTHFR P42898 methylenetetrahydrofolate reductase 1.2E-09 0.354 0.828 699 94
TLR4 O00206 toll like receptor 4 5.6E-09 0.359 0.931 674 25
FGFR2 P21802 fibroblast growth factor receptor 2 1.00 0.398 0.759 665 90
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 1.8E-03 0.352 0.862 650 53
FGFR1 P11362 fibroblast growth factor receptor 1 1.00 0.388 0.759 623 80
IL4 P05112 interleukin 4 5.3E-03 0.364 0.931 615 10
NFKB1 P19838 nuclear factor kappa B subunit 1 1.00 0.365 0.931 611 25
IL1A P01583 interleukin 1 alpha 1.5E-04 0.366 0.931 596 11
IL2 P60568 interleukin 2 0.49 0.373 0.931 564 4
FGFR3 P22607 fibroblast growth factor receptor 3 1.8E-05 0.417 0.759 558 42
POMC P01189 proopiomelanocortin 9.4E-05 0.382 0.862 557 20
NOS2 P35228 nitric oxide synthase 2 1.5E-14 0.385 0.931 531 17
FLNA P21333 filamin A 1.00 0.456 0.793 509 79
IGF2 P01344 insulin like growth factor 2 4.7E-02 0.399 0.828 505 11