Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 138 9
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 35 0
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 63 1
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 98 8
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 70 0
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 68 172
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 89 14
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2