Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 112 15
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 78 47
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 70 0
CLU P10909 clusterin 7.8E-05 0.426 0.885 66 7
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 66 6
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 63 0
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 63 1
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 61 19
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 59 21
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 52 0