Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 9 44
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 3 2
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885 3 1
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 5 1
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808 2 26
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692 6 3
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692 4 2
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808 3 4
DDR2 Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 0.55 0.541 0.769 2 4
LATS1 O95835 large tumor suppressor kinase 1 Kinase 1.00 0.563 0.731 2 1
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 5 5
NEK1 Q96PY6 NIMA related kinase 1 Kinase 1.9E-25 0.575 0.769 4 2
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462 3 0
TRIB1 Q96RU8 tribbles pseudokinase 1 Kinase 0.83 0.617 0.577 1 0
CAMK4 Q16566 calcium/calmodulin dependent protein kinase IV Kinase 0.51 0.621 0.654 2 1
EPHA5 P54756 EPH receptor A5 Kinase 7.3E-05 0.626 0.615 3 2
MYO18B Q8IUG5 myosin XVIIIB 1.0E-31 0.628 0.615 4 5
DCLK3 Q9C098 doublecortin like kinase 3 Kinase 0.14 0.647 0.615 5 2
TRPM6 Q9BX84 transient receptor potential cation channel subfamily M member 6 Kinase 2.7E-10 0.656 0.538 3 2
BMX P51813 BMX non-receptor tyrosine kinase Kinase 6.7E-03 0.663 0.385 1 1
STK33 Q9BYT3 serine/threonine kinase 33 Kinase 2.2E-06 0.666 0.346 1 0
RPS6KA6 Q9UK32 ribosomal protein S6 kinase A6 Kinase 0.99 0.686 0.385 2 0