Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 226
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 169
IL6 P05231 interleukin 6 0.32 0.248 0.962 177
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 171
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 112
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 134
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 156
IFNG P01579 interferon gamma 0.47 0.288 0.962 91
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 83
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 85
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 100
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 118
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 84
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 20
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 84
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 37
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 59
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 50
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 67
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 95
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 88