Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACCS Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 9.0E-07 0.522 0.731 161 1
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 117 2
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692 64 2
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 138 4
PAPSS2 O95340 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Enzyme 2.0E-10 0.682 0.462 20 1
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 38 0
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 112 0
BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase 2 8.5E-08 0.700 0.462 26 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 66 0
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 30 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 83 3
NT5C Q8TCD5 5', 3'-nucleotidase, cytosolic 2.7E-03 0.729 0.231 23 0
XRN2 Q9H0D6 5'-3' exoribonuclease 2 0.35 0.821 0.269 7 1
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 361 4
NT5C1A Q9BXI3 5'-nucleotidase, cytosolic IA 8.3E-05 0.615 0.654 63 1
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 114 5
AZI2 Q9H6S1 5-azacytidine induced 2 6.9E-03 0.760 0.577 19 2
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308 23 1
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423 40 9
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 91 1
PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Enzyme 2.1E-09 0.666 0.346 36 0
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 266 37
AKAP10 O43572 A-kinase anchoring protein 10 0.11 0.760 0.308 17 2