Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
AKT1 P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 0.98 0.355 0.862 20
AKT2 P31751 AKT serine/threonine kinase 2 calcium-binding protein; kinase; transfer/carrier protein; transferase 0.61 0.512 0.655 15
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.505 0.724 7
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.561 0.655 5
ATM Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 6.0E-46 0.401 0.862 29
BAP1 Q92560 BRCA1 associated protein 1 hydrolase; protease 0.99 0.488 0.586 14
BARD1 Q99728 BRCA1 associated RING domain 1 2.2E-24 0.624 0.379 9
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 45
BRCA1 P38398 BRCA1, DNA repair associated ligase 1.8E-28 0.410 0.862 14
BRCA2 P51587 BRCA2, DNA repair associated nucleic acid binding 5.5E-24 0.426 0.793 17
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 nucleic acid binding 4.8E-17 0.586 0.552 11
BTK Q06187 Bruton tyrosine kinase 1.00 0.524 0.690 5
CASP8 Q14790 caspase 8 enzyme modulator; hydrolase; protease 2.8E-06 0.443 0.793 6
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.66 0.424 0.724 8
CHEK2 O96017 checkpoint kinase 2 1.2E-23 0.494 0.621 10
EP300 Q09472 E1A binding protein p300 nucleic acid binding; transcription factor; transferase 1.00 0.489 0.828 12
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 1.8E-03 0.352 0.862 22
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 1.00 0.494 0.690 6
ESR1 P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 1.00 0.355 0.897 10
FGF3 P11487 fibroblast growth factor 3 signaling molecule 9.7E-05 0.554 0.690 4
FGF4 P08620 fibroblast growth factor 4 signaling molecule 0.14 0.616 0.483 4
FGFR1 P11362 fibroblast growth factor receptor 1 1.00 0.388 0.759 9
FOXA1 P55317 forkhead box A1 nucleic acid binding; transcription factor 0.24 0.590 0.586 5
GATA3 P23771 GATA binding protein 3 nucleic acid binding; transcription factor 0.90 0.477 0.793 4