Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 48
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 170
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 120
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 218
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 148
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 139
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 79
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 60
ATN1 P54259 atrophin 1 1.00 0.409 0.885 70
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 65
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 49
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846 44
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808 51
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 147