Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 80
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 147
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 38
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 160
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808 158
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 104
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 220
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 200
SLC26A4 O43511 solute carrier family 26 member 4 Transporter 9.0E-22 0.507 0.885 46
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 111
SLC9A6 Q92581 solute carrier family 9 member A6 Transporter 1.00 0.516 0.846 82
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692 113
SLC35A2 P78381 solute carrier family 35 member A2 Transporter 0.72 0.525 0.808 116
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731 21
CSTB P04080 cystatin B Enzyme modulator 6.6E-03 0.530 0.692 33
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769 111
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769 141
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769 148
EMD P50402 emerin 0.93 0.542 0.731 54
COL7A1 Q02388 collagen type VII alpha 1 chain Receptor 2.4E-40 0.545 0.808 113