Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692 3
ADIPOR1 Q96A54 adiponectin receptor 1 Receptor 0.66 0.529 0.808 7
ADIPOR2 Q86V24 adiponectin receptor 2 Receptor 0.36 0.564 0.731 6
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
ARG2 P78540 arginase 2 Enzyme 1.8E-04 0.569 0.731 10
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 20
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 20
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 13
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 21
C6 P13671 complement C6 5.9E-22 0.700 0.615 6
CYBA P13498 cytochrome b-245 alpha chain 8.9E-06 0.520 0.769 10
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 12
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 14
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 8