Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654 1
AGPAT2 O15120 1-acylglycerol-3-phosphate O-acyltransferase 2 1.2E-07 0.585 0.654 3
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 4
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692 2
OAS1 P00973 2'-5'-oligoadenylate synthetase 1 Enzyme 3.4E-05 0.626 0.654 4
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 2
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 5
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 3
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538 3
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 1
ALAS1 P13196 5'-aminolevulinate synthase 1 Enzyme 0.11 0.705 0.462 2
ALAS2 P22557 5'-aminolevulinate synthase 2 Enzyme 1.00 0.606 0.577 2
NT5DC3 Q86UY8 5'-nucleotidase domain containing 3 Enzyme 1.5E-07 0.821 0.192 1
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 4
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 1
NT5C3A Q9H0P0 5'-nucleotidase, cytosolic IIIA Enzyme 1.5E-02 0.593 0.692 1
ATIC P31939 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Enzyme 3.0E-19 0.576 0.731 1
HTOR 5-hydroxytryptamine (serotonin) oxygenase regulator 1.000 0.077 1
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 13
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 3
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308 1
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 16
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538 4
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 5