Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 69 0
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 63 0
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923 55 0
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 52 0
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846 44 0
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 32 0
NCOA3 Q9Y6Q9 nuclear receptor coactivator 3 Kinase 0.54 0.522 0.654 32 0
MIR21 microRNA 21 0.363 0.846 28 0
GPX3 P22352 glutathione peroxidase 3 Enzyme 5.1E-02 0.522 0.769 27 0
ID3 Q02535 inhibitor of DNA binding 3, HLH protein Transcription factor 0.72 0.615 0.692 27 0
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885 25 0
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885 21 0
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808 21 0
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 19 0
HOXB9 P17482 homeobox B9 0.31 0.572 0.654 15 0
PRSS8 Q16651 serine protease 8 Enzyme 0.10 0.641 0.500 15 0
PAWR Q96IZ0 pro-apoptotic WT1 regulator 9.0E-02 0.542 0.846 14 0
SULT1E1 P49888 sulfotransferase family 1E member 1 2.0E-07 0.508 0.808 14 0
NAT1 P18440 N-acetyltransferase 1 Enzyme 1.9E-14 0.536 0.846 14 0
FOXA1 P55317 forkhead box A1 Transcription factor 0.22 0.522 0.731 13 0
APPL2 Q8NEU8 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 1.2E-18 0.700 0.423 12 0
UGT2B17 O75795 UDP glucuronosyltransferase family 2 member B17 9.7E-08 0.641 0.577 12 0