Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HEATR4 Q86WZ0 HEAT repeat containing 4 1.4E-29 2
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 107
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 80
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 91
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 51
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 89
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 170
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846 38
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 79
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 97
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 326
ELN P15502 elastin 2.1E-14 0.415 0.885 257
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846 53
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846 123