Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL6 P05231 interleukin 6 0.32 0.248 0.962 262
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 182
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 178
IFNA2 P01563 interferon alpha 2 0.442 0.885 169
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
INS P01308 insulin 0.30 0.445 0.923 153
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 135
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 111
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 107
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 106
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 105
LEP P41159 leptin 0.46 0.349 0.846 104
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 98
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 96
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846 95
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 87
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 86
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 85