Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 75
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 12
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 15
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 26
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 21
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808 21