Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 425
FLNA P21333 filamin A 1.00 0.419 0.846 298
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 219
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 214
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 213
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 205
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 202
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 193
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 189
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 180
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 179
POMT1 Q9Y6A1 protein O-mannosyltransferase 1 4.2E-17 0.525 0.615 177
FKRP Q9H9S5 fukutin related protein 9.8E-06 0.513 0.731 177
FLNB O75369 filamin B 6.1E-10 0.458 0.923 173
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769 171
TRNS1 tRNA 0.555 0.808 170
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808 167
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 162
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 159
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769 158
POMT2 Q9UKY4 protein O-mannosyltransferase 2 9.4E-12 0.544 0.615 157
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 157
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 154
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 154