Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 89 14
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 78 47
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846 75 62
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 70 0
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 68 172
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 68 157
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 68 14
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 67 6
CLU P10909 clusterin 7.8E-05 0.426 0.885 66 7
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 66 6
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 63 1
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 63 0
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 61 19
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 59 21
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846 58 2
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885 57 0
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885 56 22
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 54 21
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 52 1
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 52 0