Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FLNA P21333 filamin A 1.00 0.419 0.846 7 21
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 7 15
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 7 13
TGFBI Q15582 transforming growth factor beta induced Signaling 6.0E-08 0.484 0.769 7 13
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692 7 11
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731 7 10
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692 6 132
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 6 100
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 6 70
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 6 43
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 6 40
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 6 35
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692 6 22
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692 6 20
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 6 19
PAX6 P26367 paired box 6 1.00 0.450 0.769 6 12
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 6 11
PRPS1 P60891 phosphoribosyl pyrophosphate synthetase 1 Kinase 0.92 0.584 0.731 6 9
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 6 7
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 6 6
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692 6 3
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 5 110