Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 33
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692 9
MAP3K13 O43283 mitogen-activated protein kinase kinase kinase 13 Kinase 0.80 0.743 0.192 4
NCOR1 O75376 nuclear receptor corepressor 1 Transcription factor 1.00 0.597 0.731 4
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 16
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 15
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 8
PBRM1 Q86U86 polybromo 1 Epigenetic regulator 1.00 0.566 0.615 5
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 4
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 33
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 7
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 27
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 13
SMARCD1 Q96GM5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Nucleic acid binding 1.00 0.695 0.385 4
TBX3 O15119 T-box transcription factor 3 Transcription factor 0.99 0.525 0.769 4
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 39