Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 193
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846 191
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846 191
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 187
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808 187
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 186
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846 185
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769 182
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 181
TRNW tRNA 0.563 0.731 181
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731 179
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769 178
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846 174
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 174
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 173
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 171
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 170
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808 169
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769 168
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808 167
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769 167
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769 163