Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769 111
PIGQ Q9BRB3 phosphatidylinositol glycan anchor biosynthesis class Q Enzyme 1.4E-06 0.610 0.577 111
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654 110
IRF2BPL Q9H1B7 interferon regulatory factor 2 binding protein like 0.84 0.631 0.462 108
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885 107
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 104
UNC80 Q8N2C7 unc-80 homolog, NALCN channel complex subunit 5.2E-02 0.626 0.462 103
PHIP Q8WWQ0 pleckstrin homology domain interacting protein Epigenetic regulator 1.00 0.595 0.769 102
SLC25A1 P53007 solute carrier family 25 member 1 Transporter 5.9E-02 0.553 0.731 101
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808 99
MAN1B1 Q9UKM7 mannosidase alpha class 1B member 1 Chaperone 1.2E-08 0.606 0.577 98
COL6A2 P12110 collagen type VI alpha 2 chain Receptor 6.5E-08 0.599 0.692 97
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462 93
GATAD2B Q8WXI9 GATA zinc finger domain containing 2B Nucleic acid binding 1.00 0.593 0.654 92
SLC9A6 Q92581 solute carrier family 9 member A6 Transporter 1.00 0.516 0.846 82
SRD5A3 Q9H8P0 steroid 5 alpha-reductase 3 2.5E-04 0.604 0.692 82
ANTXR2 P58335 ANTXR cell adhesion molecule 2 Receptor 8.7E-02 0.568 0.808 81
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 80
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654 79
NPHP3-ACAD11 NPHP3-ACAD11 readthrough (NMD candidate) 0.663 0.577 78
FUCA1 P04066 alpha-L-fucosidase 1 2.7E-08 0.623 0.577 74
SOX5 P35711 SRY-box transcription factor 5 1.00 0.545 0.769 73
TANGO2 Q6ICL3 transport and golgi organization 2 homolog 1.5E-04 0.666 0.615 73
IGHMBP2 P38935 immunoglobulin mu DNA binding protein 2 3.0E-16 0.636 0.615 72