Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LEP P41159 leptin 0.46 0.349 0.846 78
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 77
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 77
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 76
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 72
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 71
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 71
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 67
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 67
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 66
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 66
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 65
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 64
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 64
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 63
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 62
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 61
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 61
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 60
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 59
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 59
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 58
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 55