Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 20
MPZ P25189 myelin protein zero 0.27 0.503 0.846 12
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885 12
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769 10
SBF2 Q86WG5 SET binding factor 2 Enzyme 6.4E-10 0.619 0.577 10
DHTKD1 Q96HY7 dehydrogenase E1 and transketolase domain containing 1 2.8E-30 0.711 0.385 9
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 9
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538 9
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 9
COX6A1 P12074 cytochrome c oxidase subunit 6A1 Enzyme 2.3E-03 0.780 0.154 8
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769 8
FGD4 Q96M96 FYVE, RhoGEF and PH domain containing 4 Enzyme modulator 9.8E-03 0.678 0.462 8
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500 8
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731 8
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808 8
LRSAM1 Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 3.1E-13 0.638 0.500 8
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538 8
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731 8
NEFL P07196 neurofilament light 0.488 0.769 8
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385 8
SLC12A6 Q9UHW9 solute carrier family 12 member 6 Transporter 1.1E-02 0.603 0.500 8