Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 6.1E-18 0.636 0.414 33 18
SH2B3 Q9UQQ2 SH2B adaptor protein 3 6.7E-05 0.575 0.552 22 8
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.743 0.276 20 5
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.5E-02 0.639 0.483 18 98
TOMM40 O96008 translocase of outer mitochondrial membrane 40 membrane traffic protein 0.99 0.636 0.483 18 20
FTO Q9C0B1 FTO, alpha-ketoglutarate dependent dioxygenase 1.1E-07 0.519 0.828 17 64
ATXN2 Q99700 ataxin 2 nucleic acid binding 0.94 0.534 0.621 17 24
CDKN2B-AS1 CDKN2B antisense RNA 1 0.550 0.586 16 137
FADS1 O60427 fatty acid desaturase 1 0.41 0.636 0.621 14 15
FADS2 O95864 fatty acid desaturase 2 1.00 0.627 0.552 12 84
ALDH2 P05091 aldehyde dehydrogenase 2 family member oxidoreductase 2.5E-09 0.481 0.862 12 4
ZPR1 O75312 ZPR1 zinc finger 0.762 0.276 11 20
ZNRD1ASP zinc ribbon domain containing 1 antisense, pseudogene 0.762 0.414 11 14
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.551 0.552 11 11
NAA25 Q14CX7 N(alpha)-acetyltransferase 25, NatB auxiliary subunit transferase 1.00 0.642 0.552 11 3
CARMIL1 Q5VZK9 capping protein regulator and myosin 1 linker 1 nucleic acid binding; transcription factor 0.785 0.241 10 108
CETP P11597 cholesteryl ester transfer protein 1.0E-23 0.555 0.655 10 69
LDLR P01130 low density lipoprotein receptor 9.4E-24 0.475 0.828 10 22
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit receptor; transporter 1.2E-07 0.584 0.448 10 17
TCF7L2 Q9NQB0 transcription factor 7 like 2 0.99 0.538 0.621 10 14
LPA P08519 lipoprotein(a) hydrolase; protease 5.8E-88 0.489 0.655 10 6
CNNM2 Q9H8M5 cyclin and CBS domain divalent metal cation transport mediator 2 0.99 0.619 0.345 10 5
ABCA1 O95477 ATP binding cassette subfamily A member 1 transporter 3.5E-12 0.484 0.793 9 34
HNF1A P20823 HNF1 homeobox A nucleic acid binding; transcription factor 0.96 0.515 0.621 9 22