Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TSBP1-AS1 TSBP1 and BTNL2 antisense RNA 1 0.638 0.692 39 318
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 24 100
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 18 140
BTNL2 Q9UIR0 butyrophilin like 2 Enzyme modulator 8.6E-11 0.546 0.808 18 58
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 15 14
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 14 28
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 14 12
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615 13 11
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 13 4
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 12 11
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692 12 8
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 11 20
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 10 24
C1orf141 Q5JVX7 chromosome 1 open reading frame 141 3.2E-03 0.691 0.385 10 18
THADA Q6YHU6 THADA armadillo repeat containing Receptor 4.6E-41 0.686 0.500 9 24
ZNF365 Q70YC4 Q70YC5 zinc finger protein 365 4.7E-04 0.641 0.654 9 15
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 9 12
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 9 11
PUS10 Q3MIT2 pseudouridine synthase 10 7.9E-14 0.736 0.346 9 6
JAZF1 Q86VZ6 JAZF zinc finger 1 0.90 0.582 0.654 8 10
MIR3936HG MIR3936 host gene 0.861 0.269 8 8
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 8 4