Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 29
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 23
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 15
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846 14
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423 12