Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 26
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 16
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 15
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 14
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577 13
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 13
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885 12
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 12
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 12
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 11
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 11
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 11
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 11
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 10
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 10
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 10
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769 10
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769 10
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 10
LEP P41159 leptin 0.46 0.349 0.846 10
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 10