Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 334
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 280
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 182
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 170
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 169
INS P01308 insulin 0.30 0.445 0.923 153
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 146
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 135
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 133
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 110
LEP P41159 leptin 0.46 0.349 0.846 104
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 97
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 85
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 79
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 77
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 71
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 66
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 66
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 65
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 59
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 59
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57