Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654 19
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 18
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808 18
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 17
F7 P08709 coagulation factor VII Enzyme 1.3E-05 0.623 0.615 16
SLC9A1 P19634 solute carrier family 9 member A1 Transporter 0.79 0.550 0.731 15
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 14
ALAD P13716 aminolevulinate dehydratase Enzyme 5.6E-05 0.556 0.615 13
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923 13
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 13
PCSK1 P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 2.7E-09 0.548 0.615 11
UCP3 P55916 uncoupling protein 3 Transporter 9.6E-10 0.619 0.577 11
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 10