Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 334
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 185
IFNA2 P01563 interferon alpha 2 0.442 0.885 169
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 145
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 102
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 97
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 96
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 89
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 84
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846 74
IL2 P60568 interleukin 2 0.48 0.336 0.885 73
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 73
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 66
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 66
CLU P10909 clusterin 7.8E-05 0.426 0.885 65
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 62
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 59