PTCH1 |
Q13635
|
patched 1
|
|
1.00 |
0.398 |
0.885 |
116
|
144 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
107
|
343 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
84
|
390 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
68
|
2953 |
PALB2 |
Q86YC2
|
partner and localizer of BRCA2
|
|
3.0E-19 |
0.485 |
0.769 |
48
|
393 |
CHEK2 |
O96017
|
checkpoint kinase 2
|
Kinase
|
1.2E-24 |
0.460 |
0.808 |
48
|
209 |
NF1 |
P21359
|
neurofibromin 1
|
Enzyme modulator
|
0.90 |
0.440 |
0.885 |
47
|
887 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
44
|
888 |
SMARCB1 |
Q12824
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
|
Nucleic acid binding
|
1.00 |
0.434 |
0.846 |
43
|
27 |
RET |
P07949
|
ret proto-oncogene
|
Kinase
|
1.00 |
0.392 |
0.885 |
36
|
77 |
APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
33
|
582 |
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
33
|
229 |
C11orf65 |
Q8NCR3
|
chromosome 11 open reading frame 65
|
|
2.0E-14 |
0.670 |
0.462 |
32
|
342 |
MITF |
O75030
|
melanocyte inducing transcription factor
|
|
0.98 |
0.499 |
0.808 |
25
|
24 |
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
22
|
2439 |
STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
22
|
129 |
CDKN2A |
P42771 Q8N726
|
cyclin dependent kinase inhibitor 2A
|
|
0.39 |
0.300 |
0.885 |
22
|
83 |
MRE11 |
P49959
|
MRE11 homolog, double strand break repair nuclease
|
|
1.3E-12 |
0.527 |
0.808 |
21
|
61 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
20
|
682 |
MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
18
|
577 |
FBXO11 |
Q86XK2
|
F-box protein 11
|
Enzyme
|
1.00 |
0.604 |
0.692 |
18
|
561 |
SMAD4 |
Q13485
|
SMAD family member 4
|
Transcription factor
|
1.00 |
0.401 |
0.808 |
16
|
133 |
MUTYH |
Q9UIF7
|
mutY DNA glycosylase
|
Enzyme
|
1.3E-18 |
0.521 |
0.769 |
16
|
130 |
MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
15
|
653 |