Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 41
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
IFNG P01579 interferon gamma 0.47 0.288 0.962 36
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 34
LEP P41159 leptin 0.46 0.349 0.846 34
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 33
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 32
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30