Source: MGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LEP P41159 leptin 0.46 0.349 0.846 9
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 5
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 4
BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 3.4E-12 0.593 0.692 4
BBS4 Q96RK4 Bardet-Biedl syndrome 4 1.5E-16 0.647 0.615 4
MKKS Q9NPJ1 McKusick-Kaufman syndrome 2.1E-09 0.566 0.692 4
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808 4
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692 3
PRKCI P41743 protein kinase C iota Kinase 6.8E-02 0.584 0.500 3
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808 2
ASIP P42127 agouti signaling protein Signaling 1.6E-02 0.584 0.692 2
GUCY2C P25092 guanylate cyclase 2C Kinase 1.4E-30 0.599 0.577 2
NCOA1 Q15788 nuclear receptor coactivator 1 Kinase 1.00 0.563 0.731 2
NEIL1 Q96FI4 nei like DNA glycosylase 1 5.0E-07 0.623 0.769 2
PROX1 Q92786 prospero homeobox 1 Transcription factor 1.00 0.565 0.538 2
ANGPTL6 Q8NI99 angiopoietin like 6 Signaling 2.4E-08 0.656 0.462 1
ANKRD26 Q9UPS8 ankyrin repeat domain 26 3.6E-24 0.711 0.308 1
CPE P16870 carboxypeptidase E 0.99 0.584 0.692 1
GPR12 P47775 G protein-coupled receptor 12 G-protein coupled receptor 0.36 0.931 0.115 1
KDM3A Q9Y4C1 lysine demethylase 3A Epigenetic regulator 1.00 0.599 0.654 1
MC3R P41968 melanocortin 3 receptor G-protein coupled receptor 1.0E-07 0.695 0.462 1
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423 1
PCSK1 P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 2.7E-09 0.548 0.615 1
PLSCR3 Q9NRY6 phospholipid scramblase 3 Transporter 1.000 0.077 1