Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 37
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 33
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 33
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 31
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 29
LEP P41159 leptin 0.46 0.349 0.846 28
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 27