Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SNAP25 P60880 synaptosome associated protein 25 membrane traffic protein 0.99 0.536 0.655 6
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 0.71 0.443 0.793 5
NCSTN Q92542 nicastrin 1.00 0.681 0.379 5
SLC6A3 Q01959 solute carrier family 6 member 3 transporter 1.00 0.484 0.690 5
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.592 0.552 4
DTNBP1 Q96EV8 dystrobrevin binding protein 1 5.0E-06 0.619 0.379 4
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 receptor; transcription factor 1.00 0.559 0.586 3
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.614 0.483 3
PLCB1 Q9NQ66 phospholipase C beta 1 calcium-binding protein; enzyme modulator; hydrolase; signaling molecule 0.97 0.652 0.448 3
SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains 3 1.00 0.594 0.448 3
TCF4 P15884 transcription factor 4 nucleic acid binding; transcription factor 1.00 0.494 0.655 3
ZIC2 O95409 Zic family member 2 transcription factor 0.98 0.607 0.586 3
AKT1 P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 0.98 0.355 0.862 2
AVPR1A P37288 arginine vasopressin receptor 1A receptor 5.5E-06 0.681 0.414 2
BACE1 P56817 beta-secretase 1 hydrolase; protease 0.88 0.616 0.517 2
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit receptor; transporter 1.5E-03 0.550 0.552 2
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 8.5E-03 0.534 0.690 2
CPLX2 Q6PUV4 complexin 2 0.54 0.713 0.172 2
CSMD1 Q96PZ7 CUB and Sushi multiple domains 1 1.00 0.639 0.379 2
CTSC P53634 cathepsin C enzyme modulator; hydrolase; protease 1.0E-07 0.600 0.586 2
GRIN1 Q05586 glutamate ionotropic receptor NMDA type subunit 1 0.99 0.630 0.448 2
LRRTM1 Q86UE6 leucine rich repeat transmembrane neuronal 1 extracellular matrix protein; receptor 0.60 0.857 0.103 2
MAGI2 Q86UL8 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.00 0.624 0.586 2
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 1.00 0.462 0.759 2