Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 20
DNAH5 Q8TE73 dynein axonemal heavy chain 5 Enzyme 4.9E-64 0.590 0.692 14
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808 6
NF2 P35240 neurofibromin 2 1.00 0.468 0.885 6
PHEX P78562 phosphate regulating endopeptidase homolog X-linked Enzyme 1.00 0.548 0.808 4
SALL4 Q9UJQ4 spalt like transcription factor 4 Transcription factor 1.00 0.489 0.769 4
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 4
CBY1 Q9Y3M2 chibby family member 1, beta catenin antagonist 1.3E-03 0.769 0.192 2
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 2
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846 2
NAGLU P54802 N-acetyl-alpha-glucosaminidase 1.4E-08 0.546 0.769 2
SH3PXD2B A1X283 SH3 and PX domains 2B 4.2E-03 0.631 0.577 2
BPIFA1 Q9NP55 BPI fold containing family A member 1 1.2E-08 0.617 0.577 1
E2F4 Q16254 E2F transcription factor 4 Nucleic acid binding 0.45 0.599 0.692 1
EYA4 O95677 EYA transcriptional coactivator and phosphatase 4 4.9E-02 0.604 0.615 1
FBXO11 Q86XK2 F-box protein 11 Enzyme 1.00 0.604 0.692 1
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 1
RPL38 P63173 ribosomal protein L38 Nucleic acid binding 0.83 0.890 0.038 1
TGIF1 Q15583 TGFB induced factor homeobox 1 Enzyme 1.0E-02 0.588 0.769 1
TP73 O15350 tumor protein p73 Transcription factor 1.00 0.449 0.808 1