Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 29
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 28
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 26
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 26
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 21
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 21
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846 19
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 19
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 19