Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NOTCH4 Q99466 notch receptor 4 2.1E-23 0.534 0.731 24 38
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 23 65
HLA-DRB9 major histocompatibility complex, class II, DR beta 9 (pseudogene) 0.682 0.654 21 47
HLA-DQA2 P01906 major histocompatibility complex, class II, DQ alpha 2 Immune response 1.0E-05 0.617 0.769 18 52
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 12 32
CSMD1 Q96PZ7 CUB and Sushi multiple domains 1 1.00 0.610 0.500 11 21
SLC17A1 Q14916 solute carrier family 17 member 1 Transporter 4.1E-16 0.760 0.462 10 160
SLC17A3 O00476 solute carrier family 17 member 3 Transporter 4.9E-22 0.769 0.385 10 59
H2AC6 Q93077 H2A clustered histone 6 Nucleic acid binding 0.60 0.821 0.269 10 18
CNNM2 Q9H8M5 cyclin and CBS domain divalent metal cation transport mediator 2 1.00 0.641 0.346 10 5
NOS1AP O75052 nitric oxide synthase 1 adaptor protein Signaling 0.61 0.608 0.423 9 42
PDE4D Q08499 phosphodiesterase 4D 1.00 0.519 0.846 9 12
CACNB2 Q08289 calcium voltage-gated channel auxiliary subunit beta 2 Ion channel 2.7E-06 0.659 0.538 9 7
TRIM26 Q12899 tripartite motif containing 26 0.18 0.705 0.577 9 6
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808 8 10
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 8 8
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 7 9
ITIH3 Q06033 inter-alpha-trypsin inhibitor heavy chain 3 Enzyme modulator 1.5E-13 0.769 0.231 6 5
SGCD Q92629 sarcoglycan delta Cellular structure 2.1E-03 0.641 0.615 6 5
LSM1 O15116 LSM1 homolog, mRNA degradation associated Enzyme 1.1E-02 0.751 0.269 6 2
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654 5 32
BORCS7-ASMT BORCS7-ASMT readthrough (NMD candidate) 0.805 0.154 5 7
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731 5 7
SDCCAG8 Q86SQ7 serologically defined colon cancer antigen 8 1.2E-11 0.619 0.577 5 5