Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 69
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 37
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 33
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 31
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 26