Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
---|---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 | 334 |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 | 280 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | 262 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | 238 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | 224 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 | 160 |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 | 148 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 | 142 |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | 135 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | 135 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | 111 | |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 | 110 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | 105 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | 98 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 | 85 |
FGF2 | P09038 | fibroblast growth factor 2 | Signaling | 1.8E-02 | 0.383 | 0.923 | 79 |
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | 76 | |
HGF | P14210 | hepatocyte growth factor | Enzyme | 1.00 | 0.374 | 0.885 | 72 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | 68 | |
ADIPOQ | Q15848 | adiponectin, C1Q and collagen domain containing | 4.6E-09 | 0.376 | 0.885 | 65 | |
NPPA | P01160 | natriuretic peptide A | 5.5E-04 | 0.505 | 0.769 | 61 | |
EPHX1 | P07099 | epoxide hydrolase 1 | 3.2E-09 | 0.500 | 0.846 | 57 | |
ICAM1 | P05362 | intercellular adhesion molecule 1 | 3.5E-02 | 0.364 | 0.962 | 56 | |
ADRB2 | P07550 | adrenoceptor beta 2 | G-protein coupled receptor | 0.53 | 0.442 | 0.923 | 52 |