Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 334
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 280
IL6 P05231 interleukin 6 0.32 0.248 0.962 262
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 160
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 148
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 142
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 135
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 110
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 105
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 98
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 85
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 79
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 76
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 72
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 68
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 65
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 56
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 52