Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
BAP1 Q92560 BRCA1 associated protein 1 hydrolase; protease 0.99 0.488 0.586 4
EGLN1 Q9GZT9 egl-9 family hypoxia inducible factor 1 0.98 0.594 0.552 4
EGLN2 Q96KS0 egl-9 family hypoxia inducible factor 2 0.74 0.624 0.586 4
EPAS1 Q99814 endothelial PAS domain protein 1 nucleic acid binding; transcription factor 0.50 0.509 0.586 4
FH P07954 fumarate hydratase lyase 9.2E-02 0.533 0.690 4
GDNF P39905 glial cell derived neurotrophic factor signaling molecule 0.20 0.463 0.759 4
KIF1B O60333 kinesin family member 1B cytoskeletal protein 1.00 0.548 0.586 4
KMT2D O14686 lysine methyltransferase 2D 1.00 0.520 0.724 4
MAX P61244 MYC associated factor X nucleic acid binding; transcription factor 0.85 0.604 0.586 4
MDH2 P40926 malate dehydrogenase 2 oxidoreductase 6.7E-03 0.627 0.483 4
MERTK Q12866 MER proto-oncogene, tyrosine kinase 2.7E-11 0.557 0.690 4
MET P08581 MET proto-oncogene, receptor tyrosine kinase 0.99 0.405 0.793 4
MITF O75030 melanogenesis associated transcription factor 1.00 0.526 0.690 4
RET P07949 ret proto-oncogene 1.00 0.418 0.724 4
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A oxidoreductase 2.1E-10 0.550 0.621 4
SDHAF2 Q9NX18 succinate dehydrogenase complex assembly factor 2 3.8E-06 0.627 0.483 4
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B oxidoreductase 3.4E-04 0.513 0.690 4
SDHC Q99643 succinate dehydrogenase complex subunit C 2.1E-04 0.547 0.690 4
SDHD O14521 succinate dehydrogenase complex subunit D transfer/carrier protein 0.21 0.499 0.793 4
TMEM127 O75204 transmembrane protein 127 1.3E-02 0.701 0.414 4
VHL P40337 von Hippel-Lindau tumor suppressor 5.5E-02 0.464 0.586 4