Source: ORPHANET

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 14
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808 9
SOX3 P41225 SRY-box transcription factor 3 Transcription factor 0.45 0.535 0.731 7
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808 5
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 5
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769 4
HESX1 Q9UBX0 HESX homeobox 1 8.0E-04 0.561 0.654 4
PROKR2 Q8NFJ6 prokineticin receptor 2 G-protein coupled receptor 2.4E-06 0.538 0.731 3
ARNT2 Q9HBZ2 aryl hydrocarbon receptor nuclear translocator 2 Transcription factor 0.99 0.599 0.731 2
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 2
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808 2
KISS1R Q969F8 KISS1 receptor G-protein coupled receptor 0.44 0.515 0.769 2
WDR11 Q9BZH6 WD repeat domain 11 1.4E-08 0.524 0.808 2
ANOS1 P23352 anosmin 1 1.00 0.537 0.769 1
CCDC141 Q6ZP82 coiled-coil domain containing 141 1.6E-33 0.666 0.538 1
DUSP6 Q16828 dual specificity phosphatase 6 0.98 0.511 0.846 1
FEZF1 A0PJY2 FEZ family zinc finger 1 0.95 0.628 0.654 1
FGF17 O60258 fibroblast growth factor 17 Signaling 0.96 0.593 0.692 1
FLRT3 Q9NZU0 fibronectin leucine rich transmembrane protein 3 0.22 0.659 0.615 1
HS6ST1 O60243 heparan sulfate 6-O-sulfotransferase 1 Enzyme 0.92 0.617 0.731 1
IL17RD Q8NFM7 interleukin 17 receptor D 1.1E-06 0.617 0.654 1
NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor 0.26 0.606 0.692 1
PROK2 Q9HC23 prokineticin 2 Signaling 1.4E-02 0.555 0.769 1
SEMA3A Q14563 semaphorin 3A Signaling 0.98 0.500 0.808 1