Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 6.1E-18 0.636 0.414 68 8
ATXN2 Q99700 ataxin 2 nucleic acid binding 0.94 0.534 0.621 36 9
SH2B3 Q9UQQ2 SH2B adaptor protein 3 6.7E-05 0.575 0.552 36 8
TERT O14746 telomerase reverse transcriptase nucleic acid binding 1.00 0.393 0.828 34 16
FADS1 O60427 fatty acid desaturase 1 0.41 0.636 0.621 34 11
JMJD1C Q15652 jumonji domain containing 1C transcription factor 1.00 0.596 0.621 28 31
LPP Q93052 LIM domain containing preferred translocation partner in lipoma cell junction protein; cytoskeletal protein; enzyme modulator 8.8E-03 0.588 0.552 28 19
PVT1 Pvt1 oncogene 0.555 0.552 27 13
SMAD3 P84022 SMAD family member 3 transcription factor 0.84 0.462 0.862 27 12
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.743 0.276 26 5
THADA Q6YHU6 THADA, armadillo repeat containing receptor 1.1E-37 0.707 0.414 25 17
C5orf56 Q8N8D9 chromosome 5 open reading frame 56 4.4E-03 0.701 0.276 25 14
CLEC16A Q2KHT3 C-type lectin domain containing 16A 0.19 0.619 0.586 23 24
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.596 0.586 23 18
PTPN22 Q9Y2R2 protein tyrosine phosphatase, non-receptor type 22 3.6E-19 0.497 0.793 22 1
SIK3 Q9Y2K2 SIK family kinase 3 kinase; transferase 1.00 0.752 0.310 21 8
MIR3936HG MIR3936 host gene 0.928 0.069 20 13
BCL2 P10415 BCL2, apoptosis regulator signaling molecule 0.57 0.312 0.862 20 7
SLC22A4 Q9H015 solute carrier family 22 member 4 1.3E-08 0.676 0.483 19 11
FADS2 O95864 fatty acid desaturase 2 1.00 0.627 0.552 18 10
IL21-AS1 IL21 antisense RNA 1 0.720 0.207 18 5
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.713 0.310 17 14
TNXB P22105 tenascin XB 0.18 0.598 0.621 17 12
PRTFDC1 Q9NRG1 phosphoribosyl transferase domain containing 1 isomerase; transferase 2.7E-13 0.785 0.310 17 8