Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 27
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26
IFNG P01579 interferon gamma 0.47 0.288 0.962 25
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 23
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 23
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 20
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 16
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846 15