Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 12 18
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
BMPR1B O00238 bone morphogenetic protein receptor type 1B Kinase 1.00 0.573 0.615 5 7
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 5 5
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692 4 71
GUCY2D Q02846 guanylate cyclase 2D, retinal Kinase 6.5E-10 0.570 0.769 4 20
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692 4 13
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 4 11
MAP3K15 Q6ZN16 mitogen-activated protein kinase kinase kinase 15 2.9E-32 0.792 0.231 4 1
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692 4 1
EPHA8 P29322 EPH receptor A8 Kinase 1.8E-10 0.686 0.346 4 0
TAF1 P21675 TATA-box binding protein associated factor 1 Kinase 1.00 0.581 0.808 3 5
WNK4 Q96J92 WNK lysine deficient protein kinase 4 Kinase 6.9E-25 0.644 0.538 3 4
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846 3 3
SIK1 A0A0B4J2F2 P57059 salt inducible kinase 1 Kinase 0.94 0.544 0.731 3 2
GUCY2C P25092 guanylate cyclase 2C Kinase 1.4E-30 0.599 0.577 3 2
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769 3 2
PAK5 Q9P286 p21 (RAC1) activated kinase 5 Kinase 1.00 0.631 0.462 3 2
EPHA7 Q15375 EPH receptor A7 Kinase 1.00 0.619 0.500 3 1
MAST1 Q9Y2H9 microtubule associated serine/threonine kinase 1 Kinase 1.00 0.711 0.385 3 1
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 3 1
PKN1 Q16512 protein kinase N1 Kinase 0.20 0.647 0.692 3 1